TRMT11 — TRNA methyltransferase 11 homolog
TRMT11 belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TRMT11's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Colonocytes | Transcription-Coupled Splicing RNA processing & translation | ANKRD26, ANKRD36, ANKS3, C1orf35, CDK10, CDK12, CHD6, CWF19L2 +31 more | View in SCUBA |
About the gene
| Synonyms | C6orf75, dJ187J11.2, MDS024, TRM11, TRMT11-1 |
|---|---|
| Chromosome | 6: 125986479-126203817 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Metabolic proteins, Predicted intracellular proteins |
| Molecular function | Methyltransferase, RNA-binding, Transferase, tRNA-binding |
| Biological process | tRNA processing |
Function
Catalytic subunit of the TRMT11-TRM112 methyltransferase complex, that specifically mediates the S-adenosyl-L-methionine- dependent N(2)-methylation of guanosine nucleotide at position 10 (m2G10) in tRNAs. This is one of the major tRNA (guanine-N(2))-methyltransferases
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.