AIFM3 — Apoptosis inducing factor mitochondria associated 3
AIFM3 belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
AIFM3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Colonocytes | Crypt Colonocyte Identity Epithelial development | ABCA2, ADGRA3, ARHGAP44, CFTR, CYP27A1, EDIL3, EPHX2, NECAB3 +7 more | View in SCUBA |
About the gene
| Synonyms | AIFL, FLJ30473 |
|---|---|
| Chromosome | 22: 20965108-20981360 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Molecular function | Oxidoreductase |
| Biological process | Apoptosis, Electron transport, Transport |
Function
Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.