EDIL3 — EGF like repeats and discoidin domains 3
EDIL3 belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
EDIL3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Angiogenic Endothelial Identity Endothelial cell development | ADAMTSL2, ARHGAP29, COL13A1, CTNNB1, EML1, ETS1, EXOC3L1, FHOD1 +14 more | View in SCUBA |
| Fibroblasts | Subepithelial Fibroblast Developmental | A2M, ABCA10, ABCA6, ABCA8, ABCA9, ADAMDEC1, CFD, CTSC +8 more | View in SCUBA |
| Goblet cells | Colonocyte Differentiation Program Epithelial development | ASCL2, CAMK1D, CDK6, ENTPD5, FOXN3, HMGCS2, IRF2BP2, KLF5 +8 more | View in SCUBA |
| Pericytes | Pericyte Identity Developmental | ADAMDEC1, EMID1, FOXF1, IL1R1, LRP1, LTBP4, MXRA5, NR2F1 +2 more | View in SCUBA |
| Smooth muscle cells | Notch-TGFbeta Signaling Development | AHI1, CD81, CD9, CPED1, FHL1, GSN, JUND, MAF +3 more | View in SCUBA |
About the gene
| Synonyms | DEL1 |
|---|---|
| Chromosome | 5: 83940554-84384880 |
| Predicted location | Secreted |
| Essential gene | No |
| Protein class | Predicted secreted proteins |
| Molecular function | Developmental protein |
| Biological process | Cell adhesion |
Function
Promotes adhesion of endothelial cells through interaction with the alpha-v/beta-3 integrin receptor. Inhibits formation of vascular-like structures. May be involved in regulation of vascular morphogenesis of remodeling in embryonic development
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.