CSTPP1 — Centriolar satellite-associated tubulin polyglutamylase complex regulator 1
CSTPP1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CSTPP1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Enterocytes | Long-gene transcript bias Technical artifact | CBLB, GALNT6, GSDME, LARGE1, PLXNA2, RAD51B | View in SCUBA |
About the gene
| Synonyms | C11orf49, FLJ22210, MGC4707 |
|---|---|
| Chromosome | 11: 46936689-47164385 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
Function
Regulator of the tubulin polyglutamylase complex (TPGC) that controls cytoskeletal organization, nuclear shape, and cilium disassembly by balancing microtubule and actin assembly. Regulates the assembly and stability of the TPGC and thereby modulates polyglutamylation of the microtubule, which antagonizes MAP4 binding
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.