JKAMP — JNK1/MAPK8 associated membrane protein
JKAMP belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
JKAMP's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Macrophages | Autophagy Vesicular Trafficking Vesicular traficking | ACTR2, AHCYL1, ALKBH5, BECN1, BICD2, CAP1, CAPRIN1, COLGALT1 +32 more | View in SCUBA |
About the gene
| Synonyms | C14orf100, CDA06, HSPC213, HSPC327, JAMP |
|---|---|
| Chromosome | 14: 59484443-59505410 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Cancer-related genes, Predicted membrane proteins |
| Biological process | Unfolded protein response |
Function
Regulates the duration of MAPK8 activity in response to various stress stimuli (By similarity). Facilitates degradation of misfolded endoplasmic reticulum (ER) proteins through the recruitment of components of the proteasome and endoplasmic reticulum-associated degradation (ERAD) system
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.