NDUFS4 — NADH:ubiquinone oxidoreductase subunit S4
NDUFS4 belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
NDUFS4's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Colonocytes | Oxidative Phosphorylation Mitochondrial & OxPhos | ATP5MF, ATP5PD, CHCHD2, COX4I1, COX5A, COX6C, COX7B, COX7C +28 more | View in SCUBA |
About the gene
| Synonyms | AQDQ, CI-18 |
|---|---|
| Chromosome | 5: 53560633-53683338 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins |
| Biological process | Electron transport, Respiratory chain, Transport |
Function
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.