CHCHD2 — Coiled-coil-helix-coiled-coil-helix domain containing 2

CHCHD2 belongs to a gene co-expression module in 14 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

CHCHD2's module in each cell type

About the gene

Function

Transcription factor. Binds to the oxygen responsive element of COX4I2 and activates its transcription under hypoxia conditions (4% oxygen), as well as normoxia conditions (20% oxygen)

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.