NKD1 — NKD inhibitor of WNT signaling pathway 1
NKD1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
NKD1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | ICC contractility Gut motility | BEX1, BTC, DES, HACD1, HSPB7, IL17B, KCNMA1, LDB3 +7 more | View in SCUBA |
About the gene
| Chromosome | 16: 50548396-50649249 |
|---|---|
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Biological process | Wnt signaling pathway |
Function
Cell autonomous antagonist of the canonical Wnt signaling pathway. May activate a second Wnt signaling pathway that controls planar cell polarity.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.