NUP42 — Nucleoporin 42
NUP42 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
NUP42's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | Ubiquitin-Proteasome Trafficking Protein processing & ER | ARHGEF9, DDX50, DENND10, FBXL6, LIMK1, MTG1, PEX2, RNF187 +8 more |
About the gene
| Synonyms | CG1, H_RG271G13.9, hCG1, NLP_1, NUPL2 |
|---|---|
| Chromosome | 7: 23181841-23201011 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Metabolic proteins, Predicted intracellular proteins, Transporters |
| Biological process | mRNA transport, Protein transport, Translocation, Transport |
Function
Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. (Microbial infection) In case of infection by HIV-1, it may participate in the docking of viral Vpr at the nuclear envelope
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.