SCUBA

ARHGEF9 — Cdc42 guanine nucleotide exchange factor 9

ARHGEF9 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

ARHGEF9's module in each cell type

Cell typeModuleShares the module with
Gamma-delta T cellsUbiquitin-Proteasome Trafficking
Protein processing & ER
DDX50, DENND10, FBXL6, LIMK1, MTG1, NUP42, PEX2, RNF187 +8 more

About the gene

SynonymsKIAA0424, PEM-2
ChromosomeX: 63634967-63809274
Predicted locationIntracellular
Essential geneNo
Protein classDisease related genes, Human disease related genes, Predicted intracellular proteins
Molecular functionGuanine-nucleotide releasing factor

Function

Acts as a guanine nucleotide exchange factor (GEF) for CDC42. Promotes formation of GPHN clusters (By similarity)

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.