SCUBA

PDE8B — Phosphodiesterase 8B

PDE8B belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

PDE8B's module in each cell type

Cell typeModuleShares the module with
FibroblastsRetinoid Stromal Quiescence
Developmental
ACAN, GALNT17, KCTD8, NDUFA4L2, NTRK3, PCDH17, RBP4, RXRG +5 moreView in SCUBA

About the gene

Chromosome5: 77210449-77428256
Predicted locationIntracellular
Essential geneNo
Protein classDisease related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins
Molecular functionHydrolase

Function

Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in specific signaling in the thyroid gland

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.