SCUBA

PPWD1 — Peptidylprolyl isomerase domain and WD repeat containing 1

PPWD1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

PPWD1's module in each cell type

Cell typeModuleShares the module with
Gamma-delta T cellsDNA Damage Repair
DNA/chromatin regulation
ANKRD10, ASF1A, DDX18, DNAJC17, ENPP5, KLRC4, KLRD1, NARS1 +15 more

About the gene

SynonymsKIAA0073
Chromosome5: 65563236-65587549
Predicted locationIntracellular
Essential geneYes
Protein classEnzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins
Molecular functionIsomerase, Rotamase
Biological processmRNA processing, mRNA splicing

Function

PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding. May be involved in pre-mRNA splicing.

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.