RINL — Ras and Rab interactor like
RINL belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
RINL's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | DNA Damage Repair DNA/chromatin regulation | ANKRD10, ASF1A, DDX18, DNAJC17, ENPP5, KLRC4, KLRD1, NARS1 +15 more |
About the gene
| Synonyms | FLJ45909 |
|---|---|
| Chromosome | 19: 38867830-38878275 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Molecular function | GTPase activation |
| Biological process | Endocytosis, Protein transport, Transport |
Function
Guanine nucleotide exchange factor (GEF) for RAB5A and RAB22A that activates RAB5A and RAB22A by exchanging bound GDP for free GTP. Plays a role in endocytosis via its role in activating Rab family members (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.