SCUBA

RSAD1 — Radical S-adenosyl methionine domain containing 1

RSAD1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

RSAD1's module in each cell type

Cell typeModuleShares the module with
Gamma-delta T cellsRNA Splicing Processing
RNA processing & translation
ABCF2, ACTR1B, ARF3, C1orf35, CDK11B, DCAF8, DDX39B, EIF4EBP2 +16 more

About the gene

SynonymsFLJ11164, HemW
Chromosome17: 50478860-50485974
Predicted locationIntracellular
Essential geneYes
Protein classEssential proteins, Predicted intracellular proteins
Molecular functionChaperone

Function

May be a heme chaperone, appears to bind heme. Homologous bacterial proteins do not have oxygen-independent coproporphyrinogen- III oxidase activity (Probable). Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L- methionine (By similarity).

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.