ARF3 — ADP ribosylation factor 3
ARF3 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ARF3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | RNA Splicing Processing RNA processing & translation | ABCF2, ACTR1B, C1orf35, CDK11B, DCAF8, DDX39B, EIF4EBP2, IDH3B +16 more | |
| Innate lymphoid cells | Glycolysis & OxPhos Metabolism | ANXA7, ATP5MC3, CD320, CD74, CNBP, COX6A1, COX6B1, IL2RG +10 more | View in SCUBA |
| Macrophages | Nuclear Pore Transport Housekeeping | AARS1, APH1A, ATG3, CNOT7, CTDNEP1, DCAF7, GNAI2, HCFC1 +18 more | View in SCUBA |
About the gene
| Chromosome | 12: 48935723-48957487 |
|---|---|
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted intracellular proteins |
| Biological process | ER-Golgi transport, Protein transport, Transport |
Function
GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.