STEAP1 — STEAP family member 1
STEAP1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
STEAP1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | Activated Myofibroblast State Wound healing | BGN, BMP1, CPXM1, CTHRC1, EGFL6, FAP, KIAA0930, MASP1 +7 more | View in SCUBA |
About the gene
| Synonyms | PRSS24, STEAP |
|---|---|
| Chromosome | 7: 90154456-90164829 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Cancer-related genes, Predicted membrane proteins, Transporters |
Function
Does not function as a metalloreductase due to the absence of binding sites for the electron-donating substrate NADPH. Promotes Fe(3+) reduction when fused to the NADPH-binding domain of STEAP4
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.