ACOT11 — Acyl-CoA thioesterase 11
ACOT11 belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ACOT11's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Colonocytes | Lipid Metabolism Nutrient processing | ABCD1, ACSS2, ADAP1, AP1B1, ATP1A1, CACFD1, CAPN5, CARM1 +29 more | View in SCUBA |
About the gene
| Synonyms | BFIT, BFIT1, KIAA0707, STARD14, THEA, THEM1 |
|---|---|
| Chromosome | 1: 54542257-54639192 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Enzymes, Metabolic proteins, Predicted intracellular proteins |
| Molecular function | Hydrolase, Serine esterase |
| Biological process | Fatty acid metabolism, Lipid metabolism |
Function
Has an acyl-CoA thioesterase activity with a preference for the long chain fatty acyl-CoA thioesters hexadecanoyl-CoA/palmitoyl-CoA and tetradecanoyl-CoA/myristoyl-CoA which are the main substrates in the mitochondrial beta-oxidation pathway
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.