BCO1 — Beta-carotene oxygenase 1
BCO1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
BCO1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Enterocytes | Dietary lipid absorption Absorption | ABCG5, ASAH2, CD36, ENPP7, GATA4, LCT, LIN52, NPC1L1 +3 more | View in SCUBA |
About the gene
| Synonyms | BCDO, BCDO1, BCMO, BCMO1, FLJ10730 |
|---|---|
| Chromosome | 16: 81238689-81291142 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins |
| Molecular function | Dioxygenase, Oxidoreductase |
| Biological process | Lipid metabolism |
Function
Symmetrically cleaves beta-carotene into two molecules of retinal using a dioxygenase mechanism.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.