BCS1L — BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone
BCS1L belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
BCS1L's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Colonocytes | Mitochondrial Biogenesis Mitochondrial & OxPhos | BCAT2, CCND2, CEP70, CLUH, CRLS1, CRTAP, DNAJA3, EEF2 +28 more | View in SCUBA |
About the gene
| Synonyms | BCS, BJS, h-BCS, Hs.6719 |
|---|---|
| Chromosome | 2: 218658764-218663443 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters |
| Molecular function | Chaperone, Hydrolase |
Function
Chaperone necessary for the incorporation of Rieske iron- sulfur protein UQCRFS1 into the mitochondrial respiratory chain complex III. Plays an important role in the maintenance of mitochondrial tubular networks, respiratory chain assembly and formation of the LETM1 complex.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.