CRTAP — Cartilage associated protein
CRTAP belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CRTAP's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Innate lymphoid cells | Interferon-Stimulated Genes Inflammation | ALDOA, DAZAP2, DDX39B, EIF4B, GDI1, GNB2, GRINA, GSTM2 +17 more | View in SCUBA |
| Macrophages | Endosomal Membrane Trafficking Vesicular traficking | A2M, AP1B1, ARHGAP4, ARHGEF6, ATG4C, B3GNT7, ETV5, FYB1 +20 more | View in SCUBA |
| Monocytes | M2 Macrophage Polarization Innate immunity | AHNAK, F13A1, GLDN, GSN, IDH1, IL13RA1, LDHB, MARVELD1 +7 more | View in SCUBA |
About the gene
| Synonyms | CASP, LEPREL3, P3H5 |
|---|---|
| Chromosome | 3: 33114014-33147773 |
| Predicted location | Secreted |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted secreted proteins |
Function
Necessary for efficient 3-hydroxylation of fibrillar collagen prolyl residues
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.