SCUBA

CGREF1 — Cell growth regulator with EF-hand domain 1

CGREF1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

CGREF1's module in each cell type

Cell typeModuleShares the module with
FibroblastsTGF-beta Fibroblast Niche
ECM production
APCDD1, BAG2, C12orf75, CD55, CES1, COL11A1, CRYAB, IRS1 +8 moreView in SCUBA

About the gene

SynonymsCGR11
Chromosome2: 27098889-27119128
Predicted locationIntracellular, Membrane, Secreted
Essential geneNo
Protein classPlasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins
Biological processCell adhesion, Cell cycle, Growth arrest

Function

Mediates cell-cell adhesion in a calcium-dependent manner (By similarity). Able to inhibit growth in several cell lines

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.