CSTA — Cystatin A
CSTA belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CSTA's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Macrophages | Inflammasome Pyroptosis Inflammatory | ARRDC1, ATOX1, EMP2, ENPP2, FBXO6, GSDMD, HLA-DQB2, IL18 +12 more | View in SCUBA |
About the gene
| Synonyms | STF1, STFA |
|---|---|
| Chromosome | 3: 122325248-122341969 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins |
| Molecular function | Protease inhibitor, Thiol protease inhibitor |
| Biological process | Cell adhesion |
Function
This is an intracellular thiol proteinase inhibitor. Has an important role in desmosome-mediated cell-cell adhesion in the lower levels of the epidermis
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.