DHX8 — DEAH-box helicase 8
DHX8 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
DHX8's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | Nuclear Pore Organization Housekeeping | AIDA, H4C6, LARP1, LBR, MPRIP, MTR, NNT, NUP155 +14 more |
About the gene
| Synonyms | DDX8, Dhr2, HRH1, PRP22, PRPF22 |
|---|---|
| Chromosome | 17: 43483865-43610338 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins |
| Molecular function | Helicase, Hydrolase |
| Biological process | mRNA processing, mRNA splicing |
Function
Involved in pre-mRNA splicing as component of the spliceosome. Facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.