DOCK9 — Dedicator of cytokinesis 9
DOCK9 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
DOCK9's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Enterocytes | Long-gene nuclear transcripts Technical artifact | CCDC68, SMCHD1, SP100, UBR2, XKR9, XRN1 | View in SCUBA |
About the gene
| Synonyms | KIAA1058, ZIZ1 |
|---|---|
| Chromosome | 13: 98793429-99086625 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted intracellular proteins |
| Molecular function | Guanine-nucleotide releasing factor |
Function
Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP. Overexpression induces filopodia formation
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.