Long-gene nuclear transcripts
Gene co-expression module in Enterocytes
| Category | Technical artifact |
|---|---|
| Genes | 7 |
| Annotation certainty | 2 of 5 |
| Annotation consistency | 6 of 7 genes have a known function matching the annotation |
Why this annotation
Highly detected long genes: XRN1, DOCK9, UBR2, SMCHD1 and SP100. These are typical of a nuclear/unspliced transcript signal (long-gene intronic capture) rather than a coherent biological program. SP100 and XRN1 carry weak antiviral links. Most likely a technical nuclear-transcript signature.
Genes
CCDC68, DOCK9, SMCHD1, SP100, UBR2, XKR9, XRN1
Most correlated modules
- Junctional Hippo/TGF-beta signaling · correlation 0.86
- Apical junction complex · correlation 0.84
- Stress-responsive transcription · correlation 0.83
- TNF receptor signaling · correlation 0.82
- Epithelial junction polarity · correlation 0.82
- IFN-gamma response · correlation 0.81
- STAT3/JNK signaling · correlation 0.80
- Basal adhesion remodeling · correlation 0.77
Module annotations were drafted by a large language model from the module's genes, then reviewed and approved by a domain expert. See sources & licences.