EML3 — EMAP like 3
EML3 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
EML3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | ER Protein Biogenesis Protein processing & ER | AUP1, BAZ1B, DNAJC1, EMC10, FAM32A, FRG1, GLUD1, KLC1 +10 more |
About the gene
| Synonyms | ELP95, FLJ35827 |
|---|---|
| Chromosome | 11: 62602218-62612775 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Biological process | Cell cycle, Cell division, Mitosis |
Function
Regulates mitotic spindle assembly, microtubule (MT)- kinetochore attachment and chromosome separation via recruitment of HAUS augmin-like complex and TUBG1 to the existing MTs and promoting MT-based MT nucleation. Required for proper alignnment of chromosomes during metaphase
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.