DNAJC1 — DnaJ heat shock protein family (Hsp40) member C1
DNAJC1 belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
DNAJC1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | JAK-STAT Signaling Immune regulation | ARHGAP30, CELF2, DDX17, GSDMD, HCLS1, JAK3, MBNL1, N4BP2L2 +7 more | View in SCUBA |
| Endothelial | Actin Cytoskeletal Remodeling Cytoskeletal | ACTB, ACTG1, ARF1, ARPC5L, CFL1, CYCS, DNAJB11, ERLEC1 +5 more | View in SCUBA |
| Gamma-delta T cells | ER Protein Biogenesis Protein processing & ER | AUP1, BAZ1B, EMC10, EML3, FAM32A, FRG1, GLUD1, KLC1 +10 more | |
| Innate lymphoid cells | IFN-driven ILC1 Activation Inflammation | AFF3, AGPAT5, AKIRIN2, APMAP, ARF6, ARHGEF1, DYNLT3, ELOVL5 +21 more | View in SCUBA |
| Smooth muscle cells | SMC focal adhesion Migration & adhesion | ANXA6, ARMCX6, C1orf21, CD99, HSBP1, KANK1, MORF4L2, PFDN1 +7 more | View in SCUBA |
About the gene
| Synonyms | DNAJL1, ERdj1, MTJ1 |
|---|---|
| Chromosome | 10: 21756548-22003769 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Predicted membrane proteins, Transcription factors |
| Molecular function | Chaperone, DNA-binding |
Function
May modulate protein synthesis
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.