GPD1L — Glycerol-3-phosphate dehydrogenase 1 like
GPD1L belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
GPD1L's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Colonocytes | Colonocyte Detoxification Nutrient processing | ADORA2B, AIFM2, AKR1B10, ATL3, ATP6V0D1, CBLC, CDH17, CSTB +21 more | View in SCUBA |
About the gene
| Synonyms | KIAA0089 |
|---|---|
| Chromosome | 3: 32105689-32168709 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins |
| Molecular function | Oxidoreductase |
Function
Plays a role in regulating cardiac sodium current; decreased enzymatic activity with resulting increased levels of glycerol 3- phosphate activating the DPD1L-dependent SCN5A phosphorylation pathway, may ultimately lead to decreased sodium current; cardiac sodium current may also be reduced due to alterations of NAD(H) balance induced by DPD1L
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.