GRWD1 — Glutamate rich WD repeat containing 1
GRWD1 belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
GRWD1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Colonocytes | Ribosome Biogenesis RNA processing & translation | ALDH6A1, COMMD2, CRCP, CTNNBL1, DDI2, DHX30, ENAH, FAM98A +23 more | View in SCUBA |
About the gene
| Synonyms | GRWD, RRB1, WDR28 |
|---|---|
| Chromosome | 19: 48445841-48457022 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Essential proteins, Predicted intracellular proteins |
| Biological process | DNA replication |
Function
Histone binding-protein that regulates chromatin dynamics and minichromosome maintenance (MCM) loading at replication origins, possibly by promoting chromatin openness
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.