HES2 — Hes family bHLH transcription factor 2
HES2 belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
HES2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Colonocytes | Stress RNA Methylation Stress | AJM1, ARHGEF38, ASXL1, ATF5, ATF7IP2, CBX4, CEP164, EIF4A1 +19 more | View in SCUBA |
About the gene
| Synonyms | bHLHb40 |
|---|---|
| Chromosome | 1: 6412418-6424670 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Transcription factors |
| Molecular function | DNA-binding, Repressor |
| Biological process | Transcription, Transcription regulation |
Function
Transcriptional repressor of genes that require a bHLH protein for their transcription
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.