NEK8 — NIMA related kinase 8
NEK8 belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
NEK8's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Colonocytes | Stress RNA Methylation Stress | AJM1, ARHGEF38, ASXL1, ATF5, ATF7IP2, CBX4, CEP164, EIF4A1 +19 more | View in SCUBA |
About the gene
| Synonyms | NPHP9 |
|---|---|
| Chromosome | 17: 28725897-28743455 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins |
| Molecular function | Kinase, Serine/threonine-protein kinase, Transferase |
Function
Required for renal tubular integrity. May regulate local cytoskeletal structure in kidney tubule epithelial cells. May regulate ciliary biogenesis through targeting of proteins to the cilia. Plays a role in organogenesis, and is involved in the regulation of the Hippo signaling pathway.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.