NUP93 — Nucleoporin 93
NUP93 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
NUP93's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Macrophages | Ribosome Biogenesis Cell cycle | ACAT1, ANAPC5, CFDP1, IKBIP, MGME1, MGMT, NAA15, NAA25 +8 more | View in SCUBA |
About the gene
| Synonyms | KIAA0095 |
|---|---|
| Chromosome | 16: 56730118-56850286 |
| Predicted location | Intracellular, Membrane |
| Essential gene | Yes |
| Protein class | Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters |
| Biological process | mRNA transport, Protein transport, Translocation, Transport |
Function
Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor nucleoporins, but not NUP153 and TPR, to the NPC. During renal development, regulates podocyte migration and proliferation through SMAD4 signaling.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.