PCOLCE2 — Procollagen C-endopeptidase enhancer 2
PCOLCE2 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PCOLCE2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | PI16+ Fibroblast Identity ECM production | AADACL2, ADAMTSL4, ARHGAP29, C16orf89, CADM3, CD248, CLEC3B, CYP4B1 +10 more | View in SCUBA |
About the gene
| Synonyms | PCPE2 |
|---|---|
| Chromosome | 3: 142815922-142889206 |
| Predicted location | Secreted |
| Essential gene | No |
| Protein class | Predicted secreted proteins |
| Molecular function | Heparin-binding |
Function
Binds to the C-terminal propeptide of types I and II procollagens and may enhance the cleavage of that propeptide by BMP1
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.