CADM3 — Cell adhesion molecule 3
CADM3 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CADM3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | PI16+ Fibroblast Identity ECM production | AADACL2, ADAMTSL4, ARHGAP29, C16orf89, CD248, CLEC3B, CYP4B1, F10 +10 more | View in SCUBA |
| Glial cells | Metallothionein Stress Response Stress | CLU, CTNNAL1, IFI35, MT1E, MT1M, MT2A, RARRES2, SERPINA5 +1 more | View in SCUBA |
About the gene
| Synonyms | BIgR, FLJ10698, IGSF4B, Necl-1, NECL1, SynCAM3, TSLL1 |
|---|---|
| Chromosome | 1: 159171609-159203313 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins |
| Biological process | Cell adhesion |
Function
Involved in cell-cell adhesion. Has both calcium-independent homophilic cell-cell adhesion activity and calcium-independent heterophilic cell-cell adhesion activity with IGSF4, NECTIN1 and NECTIN3. Interaction with EPB41L1 may regulate structure or function of cell-cell junctions (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.