ADAMTSL4 — ADAMTS like 4
ADAMTSL4 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ADAMTSL4's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | PI16+ Fibroblast Identity ECM production | AADACL2, ARHGAP29, C16orf89, CADM3, CD248, CLEC3B, CYP4B1, F10 +10 more | View in SCUBA |
| Macrophages | Monocyte Innate Signaling Innate immunity | IRAK1, LILRB3, MMP24OS, MYO1G, PGAP6, PLIN3, SHKBP1, STXBP2 +2 more | View in SCUBA |
About the gene
| Synonyms | DKFZP434K1772, TSRC1 |
|---|---|
| Chromosome | 1: 150549369-150560937 |
| Predicted location | Secreted |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted secreted proteins |
| Biological process | Apoptosis |
Function
Positive regulation of apoptosis. May facilitate FBN1 microfibril biogenesis.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.