POLDIP2 — DNA polymerase delta interacting protein 2
POLDIP2 belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
POLDIP2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Colonocytes | Glycosylation & Membrane Protein processing & ER | ALDH3A2, ARCN1, ATP6AP1, ATP8B1, CALCOCO2, CANT1, CD151, CERK +34 more | View in SCUBA |
About the gene
| Synonyms | DKFZP586F1524, PDIP38 |
|---|---|
| Chromosome | 17: 28346633-28357527 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Essential proteins, Predicted intracellular proteins |
| Biological process | DNA damage, DNA repair |
Function
Involved in DNA damage tolerance by regulating translesion synthesis (TLS) of templates carrying DNA damage lesions such as 8oxoG and abasic sites. May act by stimulating activity of DNA polymerases involved in TLS, such as PRIMPOL and polymerase delta (POLD1)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.