ALDH3A2 — Aldehyde dehydrogenase 3 family member A2
ALDH3A2 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ALDH3A2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Venous EC Identity Endothelial cell development | ALDH1A1, ASGR1, ATP9A, BMP2K, DSP, FAM107B, KIAA1522, LIMD2 +12 more | View in SCUBA |
| Enterocytes | Mitochondrial Energy Metabolism Mitochondrial & OxPhos | ALDH1A1, CPS1, GALM, GCNT1, GPI, GSTM4, MTCH2, NDUFV1 +2 more | View in SCUBA |
About the gene
| Synonyms | ALDH10, FALDH, SLS |
|---|---|
| Chromosome | 17: 19648136-19685760 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins |
| Molecular function | Oxidoreductase |
| Biological process | Fatty acid metabolism, Lipid metabolism |
Function
Catalyzes the oxidation of medium and long chain aliphatic aldehydes to fatty acids. Active on a variety of saturated and unsaturated aliphatic aldehydes between 6 and 24 carbons in length. Responsible for conversion of the sphingosine 1-phosphate (S1P) degradation product hexadecenal to hexadecenoic acid.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.