RAMAC — RNA guanine-7 methyltransferase activating subunit
RAMAC belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
RAMAC's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | mRNA Decay Regulation RNA processing & translation | BAG5, BAP1, BRAP, CEP120, HAUS3, IKZF5, MVD, NARF +9 more |
About the gene
| Synonyms | C15orf18, FAM103A1, HsT19360, MGC2560, RAM, RAMMET |
|---|---|
| Chromosome | 15: 82986210-82991057 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Molecular function | RNA-binding |
| Biological process | mRNA capping, mRNA processing |
Function
Regulatory subunit of the mRNA-capping methyltransferase RNMT:RAMAC complex that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs. Promotes the recruitment of the methyl donor, S- adenosyl-L-methionine, to RNMT. Regulates RNMT expression by a post-transcriptional stabilizing mechanism. Binds RNA
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.