IKZF5 — IKAROS family zinc finger 5
IKZF5 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
IKZF5's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | mRNA Decay Regulation RNA processing & translation | BAG5, BAP1, BRAP, CEP120, HAUS3, MVD, NARF, PATL1 +9 more | |
| Mucosal-associated invariant T cell | Transcription Factor Activity DNA/chromatin regulation | AKAP17A, BTAF1, HNRNPH1, HSPA9, LCOR, NDEL1, POLR2M, SDE2 +3 more |
About the gene
| Synonyms | FLJ22973, Pegasus, ZNFN1A5 |
|---|---|
| Chromosome | 10: 122990807-123008812 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors |
| Molecular function | DNA-binding, Repressor |
| Biological process | Transcription, Transcription regulation |
Function
Transcriptional repressor that binds the core 5'GNNTGTNG-3' DNA consensus sequence. Involved in megakaryocyte differentiation.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.