SELE — Selectin E
SELE belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SELE's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | NF-κB Endothelial Activation Inflammation | LITAF, NAMPT, NFKB2, NUAK2, RELB, SBNO2, SLC35F2, SRGAP1 +5 more | View in SCUBA |
About the gene
| Synonyms | CD62E, ELAM, ELAM1, ESEL |
|---|---|
| Chromosome | 1: 169722640-169764705 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins |
| Biological process | Cell adhesion |
Function
Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with SELPLG/PSGL1. May have a role in capillary morphogenesis.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.