SEMA6C — Semaphorin 6C
SEMA6C belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SEMA6C's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Capillary Endothelial Identity Endothelial cell development | ATOH8, AVPR2, BTNL9, C1QTNF9, CD300LG, CD34, CNFN, FAM13C +10 more | View in SCUBA |
About the gene
| Synonyms | KIAA1869, Sema-Y |
|---|---|
| Chromosome | 1: 151131685-151146631 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Predicted membrane proteins |
| Molecular function | Developmental protein |
| Biological process | Differentiation, Neurogenesis |
Function
Shows growth cone collapsing activity on dorsal root ganglion (DRG) neurons in vitro. May be a stop signal for the DRG neurons in their target areas, and possibly also for other neurons. May also be involved in the maintenance and remodeling of neuronal connections
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.