SLC9A2 — Solute carrier family 9 member A2
SLC9A2 belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SLC9A2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Colonocytes | Colonocyte Differentiation Epithelial development | ACADSB, ADD3, AGPAT5, DCAF7, FAM171A1, FASTKD1, GIPC2, HOOK1 +10 more | View in SCUBA |
About the gene
| Synonyms | NHE2 |
|---|---|
| Chromosome | 2: 102619553-102711355 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters |
| Biological process | Antiport, Ion transport, Sodium transport, Transport |
Function
Plasma membrane Na(+)/H(+) antiporter. Mediates the electroneutral exchange of intracellular H(+) ions for extracellular Na(+). Major apical Na(+)/H(+) exchanger in the base of the colonic crypt. Controls in the colonic crypt intracellular pH (pHi) to direct colonic epithelial cell differentiation into the absorptive enterocyte lineage at the expense of the secretory lineage (By similarity).
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.