TMEM260 — Transmembrane protein 260
TMEM260 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TMEM260's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Macrophages | Chromatin Transcriptional Regulation Housekeeping | AGO1, ARID1A, CARD8, CEPT1, CLOCK, CPSF7, CTNND1, DCAF10 +19 more | View in SCUBA |
About the gene
| Synonyms | C14orf101, FLJ20392 |
|---|---|
| Chromosome | 14: 56488354-56650606 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Disease related genes, Predicted intracellular proteins, Predicted membrane proteins |
| Molecular function | Glycosyltransferase, Transferase |
Function
O-mannosyl-transferase that transfers mannosyl residues to the hydroxyl group of serine or threonine residues of proteins. Specifically glycosylates the IPT/TIG domain of target proteins, such as MET and MST1R/RON. TMEM260- mediated O-mannosylated residues are composed of single mannose glycans that are not elongated or modified
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.