AFF2 — ALF transcription elongation factor 2
AFF2 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
AFF2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Hematopoietic progenitor cells | Myeloid Lipid Signaling Myeloid development | CLEC12A, GALC, PLD1, SGPP1, SLC24A3, TENT5A, TEX9 | |
| Neutrophils | Myeloid Maturation Developmental | CERS6, DGKG, FAF1, LRMDA, MSRB3, PKP4, RSRC1 |
About the gene
| Synonyms | FMR2, FRAXE |
|---|---|
| Chromosome | X: 148500617-149000663 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins |
| Molecular function | RNA-binding |
| Biological process | mRNA processing, mRNA splicing |
Function
RNA-binding protein. Might be involved in alternative splicing regulation through an interaction with G-quartet RNA structure
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.