AGPS — Alkylglycerone phosphate synthase
AGPS belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
AGPS's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Neutrophils | Myeloid Lipid Remodeling Developmental | ADK, ATP8A1, ATP8B4, CLTCL1, DOP1B, ERG, GPD2, HNRNPLL +3 more |
About the gene
| Synonyms | ADAP-S, ADAS, ADHAPS, ADPS, ALDHPSY |
|---|---|
| Chromosome | 2: 177392746-177567024 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins |
| Molecular function | Transferase |
| Biological process | Lipid biosynthesis, Lipid metabolism |
Function
Catalyzes the exchange of the acyl chain in acyl- dihydroxyacetonephosphate (acyl-DHAP) for a long chain fatty alcohol, yielding the first ether linked intermediate, i.e. alkyl- dihydroxyacetonephosphate (alkyl-DHAP), in the pathway of ether lipid biosynthesis
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.