ALDH9A1 — Aldehyde dehydrogenase 9 family member A1
ALDH9A1 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ALDH9A1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | Chromatin TF Regulation DNA/chromatin regulation | ARMC1, ATIC, ERAP2, HDAC7, KAT8, LTN1, PHF14, PRPF6 +10 more | |
| Innate lymphoid cells | Actin Cytoskeleton Dynamics Cytoskeleton & motility | ACTN4, APBB1IP, ARHGAP10, CDC37, CXXC5, FAM136A, FERMT3, FIP1L1 +26 more | View in SCUBA |
| Macrophages | Innate Antiviral Sensing Innate immunity | ADA2, ADPRH, APOBEC3C, BST2, C2, CAT, CD4, CHID1 +26 more | View in SCUBA |
About the gene
| Synonyms | ALDH4, ALDH7, ALDH9, E3 |
|---|---|
| Chromosome | 1: 165662216-165698562 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins |
| Molecular function | Oxidoreductase |
Function
Converts gamma-trimethylaminobutyraldehyde into gamma- butyrobetaine with high efficiency (in vitro). Can catalyze the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction, but with low efficiency. Catalyzes the oxidation of aldehydes arising from biogenic amines and polyamines.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.