SCUBA

ANO7 — Anoctamin 7

ANO7 belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

ANO7's module in each cell type

Cell typeModuleShares the module with
ColonocytesBEST4+ Colonocyte Identity
Epithelial development
ABI3BP, ADAMTS14, ADCY5, ATOH8, BEST4, BMP2K, CA7, CDK18 +33 moreView in SCUBA

About the gene

SynonymsIPCA-5, NGEP, PCANAP5, PCANAP5L, TMEM16G
Chromosome2: 241188509-241225976
Predicted locationIntracellular, Membrane
Essential geneNo
Protein classPredicted intracellular proteins, Predicted membrane proteins, Transporters
Biological processLipid transport, Transport

Function

Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide (By similarity). Does not exhibit calcium-activated chloride channel (CaCC) activity. May play a role in cell-cell interactions.

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.