BEST4 — Bestrophin 4
BEST4 belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
BEST4's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Colonocytes | BEST4+ Colonocyte Identity Epithelial development | ABI3BP, ADAMTS14, ADCY5, ANO7, ATOH8, BMP2K, CA7, CDK18 +33 more | View in SCUBA |
About the gene
| Synonyms | VMD2L2 |
|---|---|
| Chromosome | 1: 44783585-44788170 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Predicted membrane proteins, Transporters |
| Molecular function | Chloride channel, Ion channel |
| Biological process | Ion transport, Transport |
Function
Ligand-gated anion channel that allows the movement of anions across cell membranes when activated by Calcium (Ca2+). Mediates the movement of hydrogencarbonate and chloride
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.