CACNB4 — Calcium voltage-gated channel auxiliary subunit beta 4
CACNB4 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CACNB4's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Macrophages | Transcriptional Kinase Regulation Housekeeping | BNC2, CABLES1, CDK8, ENOX2, FAF1, FOXO1, INPP4B, JMY +17 more | View in SCUBA |
About the gene
| Synonyms | EJM4 |
|---|---|
| Chromosome | 2: 151832771-152099167 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters |
| Molecular function | Calcium channel, Ion channel, Voltage-gated channel |
| Biological process | Calcium transport, Ion transport, Transport |
Function
The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.