CCL28 — C-C motif chemokine ligand 28
CCL28 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CCL28's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Enterocytes | Epithelial NF-kB response Inflammation | ATP10B, CASP1, E2F3, FAM135A, GSKIP, INPP4B, LYN, MRTFA +4 more | View in SCUBA |
About the gene
| Synonyms | CCK1, MEC, SCYA28 |
|---|---|
| Chromosome | 5: 43376645-43412391 |
| Predicted location | Intracellular, Secreted |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Predicted secreted proteins |
| Molecular function | Cytokine |
| Biological process | Chemotaxis |
Function
Chemotactic activity for resting CD4, CD8 T-cells and eosinophils. Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.